News, Notes and Newsletters January 2025

    1. Natural anti-inflammatories

    The field of natural medicine is constantly evolving, with ongoing research uncovering new and innovative solutions for inflammation management.

    Palmitoylethanolamide (PEA), a naturally occurring fatty acid amide, has shown remarkable anti-inflammatory and analgesic effects, offering a promising alternative to conventional pain medications.

    Low-level laser therapy (LLLT) is another emerging modality, utilising low-intensity laser light to reduce inflammation and promote tissue healing. Additionally, infrared saunas and herbal steam baths offer gentle yet effective ways to support detoxification and alleviate inflammation. Here are 10 other cutting-edge insights:

    Nettle Tincture (Urtica dioica) has gained attention for its potent anti-inflammatory properties, supported by recent research. Nettle contains bioactive compounds like flavonoids, phenolic acids, and lectins, which inhibit pro-inflammatory cytokines and enzymes such as COX and LOX. A study in the Journal of Rheumatology found that nettle extract significantly reduces pain and inflammation in osteoarthritis patients. Additionally, research in Planta Medica shows that nettle can inhibit histamine release, making it effective for managing allergic rhinitis. The International Journal of Molecular Sciences highlights nettle's benefits for skin health, including reduced inflammation and accelerated wound healing. Nettle tincture, typically made from the plant's leaves and stems using alcohol, is usually taken in doses of 1-2 mL, 2-3 times daily. Consult a healthcare provider for personalised dosage. Nettle tincture offers a safe and effective natural alternative for managing inflammation, arthritis, allergies, and skin conditions.

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    2. Mucuna Pruriens: A Natural Dopamine Booster

    Mucuna pruriens, or velvet bean, is rich in L-dopa, a precursor to dopamine, which is crucial for mood and cognitive function. Studies show that Mucuna pruriens can effectively increase dopamine levels, improving symptoms of Parkinson's disease and enhancing mood.

    Research published in the Journal of Neurology, Neurosurgery, and Psychiatry found it as effective as synthetic L-dopa with fewer side effects. Additionally, a study in the Journal of Alternative and Complementary Medicine reported that Mucuna pruriens reduced stress and improved mood in healthy individuals.

    Typically consumed as a powder or capsule, a common dosage is 500 to 1000 mg, 1 to 2 times daily. Consult a healthcare provider for personalised dosage. Mucuna pruriens offers a natural and effective way to boost dopamine levels.

    3. Modified Citrus Pectin: A Heavy Metal Detoxifier

    Derived from citrus fruit peels, modified citrus pectin (MCP) is gaining recognition for its ability to bind and remove heavy metals from the body, particularly lead and mercury. Unlike other chelating agents, MCP doesn't deplete essential minerals. Its gentle yet effective action makes it a valuable addition to detoxification protocols.

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    4. The Benefits of Omega-7 Fatty Acids

    Research published in the Journal of Nutrition found that omega-7 fatty acids, found in sea buckthorn oil, have anti-inflammatory and antioxidant effects. The study showed that omega-7 fatty acids reduced inflammation and improved cardiovascular health in patients with metabolic syndrome.

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    5. The Anti-Aging Effects of N-Acetylcysteine (NAC)

    Research published in the Journal of Gerontology found that N-acetylcysteine (NAC), an amino acid, has anti-aging effects. The study showed that NAC reduced oxidative stress and improved cognitive function in older adults, highlighting the potential for NAC to be used as a natural remedy for age-related diseases.

    6. P53 Deficiency and DHEA: Potential for Delay

    P53, or tumor protein p53, is a critical gene that prevents cancer by regulating cell division and promoting DNA repair. P53 deficiency, often due to mutations, can lead to uncontrolled cell growth and an increased risk of various cancers, including breast, lung, and colorectal cancer.

    Dehydroepiandrosterone (DHEA), a natural hormone produced by the adrenal glands, shows promise in delaying the effects of p53 deficiency. DHEA protects cells from DNA damage and oxidative stress, which are common in p53-deficient cells. It also modulates the expression of genes involved in cell cycle regulation and apoptosis, helping to compensate for the loss of p53 function.

    A study in the Journal of the National Cancer Institute found that DHEA was associated with a lower incidence of certain cancers in individuals with p53 mutations.

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    7. Oxalates: An Overview

    Oxalates, or oxalic acid, are naturally occurring compounds found in many foods, including spinach, nuts, and chocolate. They can also be produced by the body as a waste product. High oxalate intake can lead to the formation of kidney stones, particularly in individuals with certain medical conditions or genetic predispositions. Oxalates can bind to minerals like calcium, forming insoluble salts that may accumulate in the kidneys and other tissues.

    8. Scorpion Venom: A Surprising Healer

    Scorpion venom, a complex mixture of peptides and proteins, holds promising therapeutic potential. Research has shown that certain components of scorpion venom can have anti-inflammatory, analgesic, and antimicrobial properties. For instance, some peptides in the venom can inhibit pain signals, making them potential candidates for pain management. Additionally, scorpion venom has been studied for its ability to target and destroy cancer cells, particularly in brain tumors.

    Researchers are exploring its therapeutic potential, and some studies suggest it may be effective in treating conditions such as multiple sclerosis and rheumatoid arthritis. Further research is needed to fully harness its healing benefits.

    pine sterols sterols

    9. Plant Sterols in Pine Pollen and Bio-Identical Testosterone

    Pine pollen, derived from pine trees, is rich in plant sterols, which are naturally occurring compounds that can mimic the effects of human hormones. One of the key plant sterols found in pine pollen is beta-sitosterol, which has a structure similar to testosterone. This similarity allows beta-sitosterol to interact with androgen receptors, potentially providing benefits similar to those of bio-identical testosterone.

    Benefits and Potential Uses:

    Hormonal Balance: Pine pollen may help balance testosterone levels, which can decline with age. This can improve energy, mood, and sexual function.

    Anti-Inflammatory Properties: Beta-sitosterol has anti-inflammatory effects, which can be beneficial for conditions like benign prostatic hyperplasia (BPH).

    Immune Support: Pine pollen is rich in vitamins, minerals, and antioxidants, which can support overall immune function.

    Muscle Growth and Recovery: The androgenic properties of pine pollen may aid in muscle growth and recovery, making it popular among athletes and bodybuilders.

    Considerations:

    While pine pollen shows promise, more research is needed to fully understand its effects and safety. Individuals with hormone-sensitive conditions should consult a healthcare provider before using pine pollen supplements.

    10. Laptop Warning

    If you use a laptop, use it on a table and not on your lap. The heat they generate may affect fertility.

    laptop

    11. Trump's Decision to Exit WHO: A New Chapter in Global Health

    President Donald Trump's decision to withdraw the United States from the World Health Organization (WHO) marks a significant shift in global health policy. While controversial, this move has motivated the U.S. to explore alternative ways to contribute to global health initiatives, ensuring more transparent and results-driven partnerships.

    The executive order criticises the WHO for:

    • Poor management of the Covid-19 pandemic
    • Failure to implement necessary reforms
    • Undue political influence from member states and
    • Inequitable funding, with the US contributing significantly more than other countries

    In addition the Trump administration placed a freeze on many federal health agency communications with the public, including the FDA, until at least the end of the month.

    12. Bacteria Beneficial for Longevity 

    A recent study reveals that the blood of centenarians and super-centenarians (people over 110) contains unique biomarkers linked to longevity. Researchers found the specific beneficial bacteria that contributed to longevity:

    1. Bifidobacterium:
      • Yogurt with live cultures (especially those containing Bifidobacterium bifidum or Bifidobacterium lactis)
      • Kefir (a fermented milk drink)
      • Fermented vegetables like sauerkraut, kimchi, and kefir-based sauerkraut
      • Oatmeal and other whole grains containing beta-glucans
    2. Christensenella:
      • Fermented plant-based foods like:
        • Sauerkraut
        • Kimchi
        • Miso
        • Tempeh
      • Whole grains like:
        • Brown rice
        • Quinoa
        • Whole wheat bread
      • Legumes like:
        • Lentils
        • Chickpeas
        • Black beans
    3. Faecalibacterium:
      • Prebiotic-rich foods like:
        • Asparagus
        • Onions
        • Garlic
        • Whole wheat bread
      • Polyphenol-rich foods like:
        • Berries (especially cranberries and blueberries)
        • Green tea
        • Dark chocolate
      • Fermented foods like:
        • Yogurt
        • Kefir
        • Sauerkraut
    4. Roseburia:
      • Prebiotic-rich foods like:
        • Wheat bran
        • Oats
        • Barley
        • Honey
      • Polyphenol-rich foods like:
        • Berries (especially cranberries and blueberries)
        • Green tea
        • Dark chocolate
      • Fermented foods like:
        • Yogurt
        • Kefir
        • Sauerkraut
    5. Akkermansia:
      • Polyphenol-rich foods like:
        • Berries (especially cranberries and blueberries)
        • Green tea
        • Dark chocolate
      • Fermented foods like:
        • Yogurt
        • Kefir
        • Sauerkraut
      • Omega-3 rich foods like:
        • Fatty fish (salmon, sardines, and mackerel)
        • Flaxseeds
        • Chia seeds
    6. Methanobrevibacter:
      • Fiber-rich foods like:
        • Beans and legumes
        • Whole grains
        • Fruits (especially apples and bananas)
      • Fermented foods like:
        • Yogurt
        • Kefir
        • Sauerkraut
      • Foods high in sulfur like:
        • Garlic
        • Onions
        • Cruciferous vegetables (broccoli, cauliflower, and cabbage)
    7. Odoribacter:
      • Fiber-rich foods like:
        • Whole grains
        • Fruits (especially apples and bananas)
        • Vegetables (especially carrots and sweet potatoes)
      • Fermented foods like:
        • Yogurt
        • Kefir
        • Sauerkraut
      • Foods high in polyphenols like:
        • Berries (especially cranberries and blueberries)
        • Green tea
        • Dark chocolate

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