Product Review - Sinulex Forte
woman sinusitis Product Review - Sinulex Forte
sinulex man ingredients Product Review - Sinulex Forte

SINULEX FORTE: A non-drowsy sinus, hayfever, colds and flu relief

This is an objective, independently written product review on the natural product Sinulex Forte Capsules.

The natural ingredients in Sinulex Forte Capsules have clinical data to show its efficacy in the fight against viral and bacterial infections. The result: a reduction in the severity of symptoms of nasal congestion, sinus pressure, inflammation of the sinus cavities, postnasal drip, relief from head colds and general cold and flu symptoms. This lactose-, tartrazine- and sugar-free, natural product does not contain pseudoephedrine or any stimulants such as caffeine.

Sinulex Forte Capsules is a natural product of pharmaceutical grade quality containing 300 mg L-ascorbic acid (Vitamin C), 200 mg Horseradish extract (Amorica rusticana) and 100 mg Pelargonium sidoides root extract.

LET’S HAVE A LOOK AT THE INGREDIENTS IN SINULEX FORTE

Pelargonium sidoides root extract is a clinically and pharmacologically well-documented modern plant-based medicine for upper respiratory tract infections,1,2 such as bronchitis (effectively compared to placebo for patients with acute bronchitis)3 and sinusitis.

The genus Pelargonium has been used for centuries in traditional medicine in Lesotho and South Africa with a rich ethnobotanical history,3 as well as globally in modern medicine. Also known as Kalwerbossie, fancy leaf geranium and Umckaloabo, is a member of the Geraniaceae family. The name Umckaloabo is derived from two independent Zulu words: ‘umkhuhlane’, meaning fever and cough related diseases, and ‘uhlabo’, meaning chest pain and has long been used for centuries in traditional medicine as a therapeutic remedy providing relief for a blocked or runny nose, respiratory ailments such as the common cold, secondary bacterial throat infections and viral infections such as influenza.

Extracts of the root have been available in German pharmacies since 1983 without prescription and have been widely used to treat infections of the sinuses, throat and respiratory tract.

Pelargonium’s antiviral, antimicrobial and immunomodulatory effects have also been demonstrated,4 including the inhibition of the replication of respiratory viruses. In times of infections it shows strong antibacterial qualities, as well as binding to viruses and disabling them from multiplying or mutating. Not only is pelargonium effective in alleviating symptoms of acute bronchitis, rhinosinusitis and the common cold in adults, but it shortens the duration of the disease itself.

Pelargonium’s action as a preventative agent against bacterial5 infections has been shown in a study6 published in Phytomedicine. The study observed that pelargonium inhibits adherence of bacteria to epithelial cells to protect mucous membranes from microorganisms inactivating our defence mechanisms.

The pelargonium root (also referred to as tuber) in Sinulex Forte is sourced from certified sustainable farms. Careful harvesting of this valuable root ensures compliance with Good Agricultural Practice guidelines.

Horseradish extract has been used medicinally for over 3,000 years as a decongestant herb with a robust mucolytic action. Its uses includes the relieve of nasal congestion and mucus of the respiratory tract. Horseradish contains mustard oils that irritate mucous membranes, effectively alleviating excessive accumulation of mucus. In the clinical setting, horseradish was demonstrated as having antispasmodic and anti-inflammatory effects on the respiratory tract. Allyl isothiocyanate, a constituent of horseradish, is a potent antimicrobial that may be effective in treating influenza, respiratory tract infections, and sinus inflammation. In fact, horseradish has been shown to be just as effective against several infections as standard antibiotics for treating upper respiratory con Save ditions.

Also known as kren or krenweiberl, horseradish has a long history of medicinal use in parts of Austria and Bavaria in fighting a variety of conditions including influenza, respiratory ailments, and scurvy, due to its high vitamin C content.

Interestingly, vitamin C is also used to lower, balance and maintain healthy blood histamine levels and boost the immune system. Vitamin C increases the production and activity of our immune cells, as well as prolong the survival of these cells that fight against invading viruses. Vitamin C levels in white blood cells decrease at the onset of a cold. This reflects the increased usage of vitamin C by our immune cells whilst fighting an infection. A review published in the Cochrane Central Register of Controlled Trials in 2000 revealed that vitamin C reduces the severity and duration of cold symptoms.8

Vitamin C is an essential biological antioxidant used to ameliorate a wide variety of infections and to enhance the effectiveness of the immune system. Many alternative health practitioners recommend 1g of vitamin C daily as a remedy for sinusitis.

Sinulex Forte Capsules come in packs of 3s, 10s and 30s.

Sinulex Forte Capsules Dosage

It is recommended to take this dosage for at least 5 consecutive days.

Acute

Adults and children above 12 years: take 1 capsule 3 times daily.
Children 6 – 12 years: take 1 capsule 2 times daily.

Chronic

Adults and children above 12 years: take 1 capsule 2 times a day.
Children 6 – 12 years: take 1 capsule daily or as otherwise prescribed by your healthcare professional.

Do not exceed the recommended or prescribed daily dosage.

Sinulex Forte Side-effects or warnings

  • Avoid in cases of known hypersensitivity (allergies) to any of the mentioned ingredients.
  • Safety during pregnancy and lactation has not been established.
  • Take under the supervision of a healthcare practitioner if using blood-thinning medication (e.g. warfarin). Pelargonium may increase the risk of bleeding when taken with herbs and supplements that have blood-thinning action.
  • Pelargonium contains coumarin, which may be toxic to the liver in large doses.
  • Do not use horseradish preparations in the event of having stomach or intestinal ulcers, a history of kidney disease, or a thyroid disorder.
  • Do not store above 30°C and store out of reach of children.
  • Do not use after the date of expiry.

​Sinulex Forte Capsules are available without a prescription from all leading pharmacies.

This medicine has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA). This medicine does not intend to diagnose, treat, cure, or prevent any disease or viral infections.

Sinulex capsules

References:

  1. Timmer A, Günther J, Rücker G, Motschall E, Antes G, Kern WV. Pelargonium sidoidesextract for acute respiratory tract infections. Cochrane Database of Systematic Reviews. 2008; vol. 3.
  2. Agbabiaka TB, Guo R, Ernst E. Pelargonium sidoidesfor acute bronchitis: a systematic review and meta-analysis. Phytomedicine 2008;15(5):378-385.
  3. M. Michaelis, H. Wilhelm Doerr, J. Cinatl. Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses. Phytomedicine. Issue 5, 15 2011;18(5): 384-386
  4. Kolodziej H. Antimicrobial, antiviral and immunomodulatory activity studies of Pelargonium sidoides(EPs® 7630) in the context of health promotion. Pharmaceuticals Basel 2011;4(10):1295-1314.
  5. F. B. Lewu, D. S. Grierson, and A. J. Afolayan. Extracts from Pelargonium sidoides inhibit the growth of bacteria and fungi. Pharmaceutical Biology. 2006;44(4):279–282
  6. Wittschier N, Faller G, Hensel A. An extract of Pelargonium sidoides(EPs 7630) inhibits in situ adhesion of Helicobacter pylori to human stomach. Phytomedicine 2007;14(4):285-288.
  7. Goos et al: Efficacy and safety profile of a herbal drug containing nasturtium herb and horseradish root in acute sinusitis, acute bronchitis and acute urinary tract infection in comparison with other treatments in the daily practice/results of a prospective cohort study. Arzneimittelforschung. 2006;56(3):249-57
  8. Douglas R.M. et al. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev 2000; 2:CD000980.
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