Product Review – TravelRite®

This is an objective, independently written product review on TravelRite^® tablets to support, relieve and prevent nausea, dizziness and vertigo – the natural way.

As we travel through life, we find ourselves on many different journeys. No matter what path you are on or the choice of transport, say no to nausea! Participate fully in life with TravelRite^® as your companion.

Nausea and its many causes

There are multiple pathways and causes of nausea and vomiting. Specific areas in the brain and a complex interaction of vagal sensory and motor neurons to the cortex, hypothalamus, and limbic regions plays a role in how the brain perceives nausea. Multiple chemoreceptors are involved in these pathways.

Causes may be as simple as the body’s defence against an ingested toxin (also prescription medication), anaesthesia, stress and/or fear, pregnancy, alcohol excess, psychiatric disorders and a complex association set of signals activated by motion or position.

Indications for the treatment of acute onset nausea requires astute evaluation by your medical doctor. Do not overlook surgical emergencies such as small bowel obstructions, perforated viscus, and acute appendicitis, among others.

Chronic nausea is more likely to be multi-factorial and might be more challenging to treat.

What makes TravelRite^® effective?

TravelRite^® is scientifically formulated using a combination of four botanical extracts:

1. 50 mg Gingerol (Each tablet contains 20% high-quality standardised* extract)
2. 10 mg Peppermint leaf extract
3. 15 mg Lemon bioflavonoid extract (35%)

*Delivers exactly what you need with every dose. 20% gingerol is equal to 500 mg dried ginger extract.

1. Gingerol – the major constituents of fresh ginger

Generally used to alleviate nausea, cramping, bloating and indigestion, the spice ginger works by stimulating digestive enzyme secretions in the gut.¹

This popular traditional medicine plant helps to relax the smooth muscles in your gut lining and assists with digestion by speeding up the movement of food in the intestinal tract.² Gut mobility can be problematic especially in people with diabetes, and can cause heartburn and stomach discomfort after meals. Prescription medication to increase muscle contractions in the upper digestive tract, has numerous and serious side effects.³

Studies have shown ginger to be one of the most effective remedies in treating symptoms of nausea and vomiting caused by pregnancy^4,5 and chemotherapy.^6,7 The effectiveness of ginger in preventing vomiting, has been attributed to its carminative effect, which helps to break up and expel intestinal gas.⁸ 

Why not just eat fresh ginger?

The oleoresin (oily resin) from the roots of ginger (gingerol) is a bioactive component of ginger – the primary pungent ingredient. This oily resin is reduced in dry ginger.⁹ The medicinal, chemical, and pharmacological properties of gingerol have been extensively studied and reviewed as a preventive and therapeutic agent. It is proven effective in preventing and treating a variety of pathologic conditions, including nausea and vomiting.¹⁰

Ginger protects and relieves more than just nausea

As a bonus, gingerol contains a very high level (3.85 mmol/100 g) of total antioxidants, surpassed only by pomegranate and some types of berries.¹¹  But wait – it gets even better!

Hang over cure

Should you come to experience the ill effects of too much alcohol, ginger has shown to be a natural hang over cure. The effect of alcohol on the liver related antioxidant enzyme system improved with ginger intake. Ginger plays a protective role against ethanol induced hepatotoxicity (damaged liver cells).¹²

Radio-protective effects

Ginger extract has been reported to exert radio-protective effects in mice exposed to gamma radiation (electromagnetic radiation).¹³ Gingerol pre-treatment decreases oxidative stress induced by ultraviolet B (UVB) radiation – the shorter wavelength from the sun, associated with skin burning. So take TravelRite^® when you plan on spending a long time in the sun.

Air travel exposes travellers to low levels of radiation

When flying, we are exposed to ionizing radiation, but the dose is low and depends on a few factors: duration, altitude and latitude. The farther north or south you are from the Equator, the more radiation you will receive.

Medical imaging

Ginger has been shown to reduce the post-radiation inflammatory response and delays cellular division caused by of medical imaging (ionizing radiation to generate images), allowing more time for cells to repair.¹⁴ Ginger is effective at decreasing the side effects of radiation therapy, even in low doses. Side effects of radiation includes direct DNA damage, cell death, tissue injury, malformations in an embryo or fetus and cancer.

2. Peppermint Leaf Extract

In folk medicine, according to WHO monographs, peppermint has been used for centuries in European countries, as a carminative herbal medicine, to treat diarrhoea and nausea.¹⁵

In the Indian Materia Medica (Nadkarni’s 1982), infused peppermint leaves are used in cases of vomiting.

According to the American Cancer Society’s, peppermint extract helps to control nausea after surgery. Peppermint also reduces nausea caused by chemotherapy.¹⁶

3. Lemon Bioflavonoids Extract

Bioflavonoids belong to a larger group of compounds called polyphenols and are potent antioxidants. It helps with saliva production in the mouth and relieves indigestion and  acidity. Lemon contains a neutralizing acid which forms bicarbonate compounds that helps to relieve nausea.¹⁷

DOSAGE AND DIRECTIONS FOR USE:

Take TravelRite^® Anti-Nausea Tablets 30 minutes before taking other medication, 30 minutes before food and 30 minutes before traveling. Do not exceed recommended dose.

MOTION SICKNESS  (car travel, air travel, boat or ship travel)

Adults and children 12 years and older: Take 1 – 2 tablets 30 minutes before travelling, then 1 – 2 tablet every hour as required.
Do not exceed 8 tablets per day.

Children 6 to 11 years:
Take 1 tablet 30 minutes before travelling, then 1 tablet as required. Do not exceed 4 tablets per day. Children 3 to 5 years of age:
Take 1 tablet 30 minutes before travelling, then 1 tablet as required. Do not exceed 3 tablets per day.

Children under 3 years of age: Use is not recommended.

POST- OPERATIVE NAUSEA, CHEMOTHERAPY INDUCED NAUSEA, NAUSEA IN PREGNANCY, DIGESTIVE NAUSEA.

Adults and children 12 years and older:
Take 1 – 2 tablets every hour as required. Do not exceed 8 tablets per day.

Children 6 to 11 years:
Take 1 tablet as required. Do not exceed 4 tablets per day.

Children 3 to 5 years of age:
Take 1 tablet as required. Do not exceed 3 tablets per day.

TravelRite^® is non-toxic, safe and effective in pregnancy. Always check with your doctor or pharmacist before taking medicines if you are pregnant or breastfeeding.

The information published here, does not intend to diagnose, treat, cure or prevent any disease. The product reviewed has not been evaluated by any regulatory body and is not intended to diagnose treat, cure or prevent any disease. The information given here is not meant to be a substitute for seeing a health professional. It is our opinion only, based on several years of research, in consultation with world experts. We’re sure you’ll find it useful, but please use it wisely and always exercise common sense.

References:

1. Platel K, Srinivasan K. Influence of dietary spices or their active principles on digestive enzymes of small intestinal mucosa in rats. Int J Food Sci Nutr. 1996; 47:55–59
2. Yamahara J, Huang QR, Li YH, Xu L, Fujimura H. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem & Pharmaceutical bulletin. 1990; 38:430–431.
3. https://www.drugs.com/metoclopramide.html
4. Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Obstet Gynecol. 2003; 189:1374–7.
5. Viljoen, E., Visser, J., Koen, N. et al.A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting. Nutr J. 2014; 13(20).
6. Pace, J.C. Oral ingestion of encapsulated ginger and reported self-care actions for the relief of chemotherapy-associated nausea and vomiting. Dissertation Abstracts International (SCI). 1987; 3297(8).
7. Iñaki Lete, José Allué. The Effectiveness of Ginger in the Prevention of Nausea and Vomiting during Pregnancy and Chemotherapy. Integr Med Insights. 2016; 11:11–17.
8. Wu K. L, Rayner C. K, Chuah S. K, editors. et al. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol. 2008; 20(5):436–40.
9. Jolad S. D, Lantz R. C, Chen G. J, Bates R. B, Timmermann B. N. Commercially processed dry ginger (Zingiber officinale): Composition and effects on LPS-stimulated PGE2 production.  2005; 66(13):1614–35.
10. Surh Y. J. Molecular mechanisms of chemo-preventive effects of selected dietary and medicinal phenolic substances. Mutat Res.1999; 428(1–2):305–27.
11. Halvorsen B. L, editor. et al. A systematic screening of total antioxidants in dietary plants. J Nutr. 2002; 132(3):461–71.
12. Mallikarjuna K, Sahitya Chetan P, et al. Ethanol toxicity: Rehabilitation of hepatic antioxidant defense system with dietary ginger. Fitoterapia. 2008; 79(3):174–8.
13. Jagetia G. C, Baliga M. S, Venkatesh P, Ulloor J. N. Influence of ginger rhizome (Zingiber officinale Rosc.) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat Res. 2003; 160(5):584–92.
14. Tyler A. Smith, Daniel R. Kirkpatrick et al. Radioprotective agents to prevent cellular damage due to ionizing radiation. J Transl Med. 2017; 15:232.
15. https://www.ema.europa.eu/en/medicines/herbal/menthae-piperitae-folium
16. Tayarani-Najaran Z, Talasaz-Firoozi E, et al. Antiemetic activity of volatile oil from Mentha spicata and Mentha × piperita in chemotherapy-induced nausea and vomiting.  2013; 7:290.
17. Harish Johari. Ayurvedic Healing Cuisine. Inner Traditions Bear and Company, 2000