Progesterone in some recent studies is reported to provide greater cardiovascular benefits. This is new research and the mechanism is only speculated about, but the benefits do seem to be real. These benefits are not demonstrated by progestins, making the distinction very important in evaluating news articles reporting research results.
Progesterone seems to reduce the severity of allergic reactions and allergies. As progesterone is the precursor of the corticosteroids, a group of hormones that are responsible for keeping inflammatory, and allergic and auto-immune conditions at bay, both men and women can experience relief from all these conditions. Women who suddenly seem to develop allergies to everything in sight after a hysterectomy may be demonstrating low levels of progesterone.
Progesterone is one of the best anti-cancer remedies around. Progesterone keeps oestrogen under control. It is the antagonist to oestrogen and completes the hormonal cycle. Because oestrogen is known to ‘switch on’ the BCL2 gene which is a cancer gene, it is highly dangerous when this hormone is unopposed because it causes uncontrolled cellular proliferation and formation of cancer cells. Progesterone ‘switches off’ the BCL2 gene and ‘on’ a protective gene, the P53 which protects us from cancer.
Editor's note: For more on menopause, read these three articles by Dr Bernard Brom: An in-depth Look at Early Menopause, Is Happiness Hormonal? and Menopause: It’s About More Than Just Hormones